Primobolan Injection GENESIS
The DCI of the active substance
Composition of the Preparation
1 ml solution contains
Active substance: methenolone enanthate 100 mg
Excipients: benzyl alcohol, benzyl benzoate, peach oil
Description of the preparation
Oily, transparent solution, from yellow-light to yellow.
Methenolone is an anabolic steroid. By penetrating into the cell nucleus, it stimulates the cell’s genetic apparatus, which leads to increased DNA, RNA, and structural protein synthesis activates tissue respiration chain enzymes and enhances intracellular macrophages. It stimulates anabolic processes and inhibits catabolic processes, caused by glucocorticoids. It leads to increased muscle mass, reduced fat deposits, improves tissue trophies, promotes calcium deposits in bones, retains sodium and water in the body. Hematopoietic action is determined by increased erythropoietin synthesis. Androgenic (moderate) action can contribute to the development of secondary sexual characters of the male type.
Methenolone is absorbed slowly. The maximum plasma concentration is achieved over 72 hours after intramuscular administration. Duration of action 2-4 weeks. In the blood, approximately 90% is coupled with a specific fraction of the transporting globulins. Biotransformation occurs in the liver up to various 17-ketosteroids, which after conjugation with glucuronic or sulfuric acid are eliminated with urine (about 90%). Approximately 6% of the absorbed preparation is removed with the feces in free form.
Disorders of protein synthesis, casein of different genesis; traumas, extensive burns, after infectious diseases and irradiation; muscular dystrophy, osteoporosis, negative nitrogen balance in corticosteroid therapy, hypo and aplastic anemia.
Dosage and Mode of Administration
The preparation is administered 1 ml deep intramuscularly, once every 2 weeks. When a favorable result is obtained, 1 ml is administered once every 3-4 weeks.
Hematological and lymphatic disorders: changes in the leukocyte formula.
Metabolic and nutrition disorders: retaining or stopping growth (calcifying the epiphyseal areas of tubular bone growth); in men and women – a progression of atherosclerosis, peripheral edema, impaired liver function,
Musculoskeletal disorders: pain in long tubular bones.
Disorders of the genital tract and sinus: In women – virilization symptoms, menstrual cycle disorders. In men: in the pre-pubertal period – symptoms of virilization, in the post-pubertal period – gynecomastia, priapism, and inhibition of spermatogenesis.