Arimidex (pharmacological name – anastrozole) is a newer drug developed to treat breast cancer in women. It was invented by Zeneca Pharmaceuticals and was approved for use in December 1995 in the United States. Arimidex is the first in a new third-generation aromatase inhibitors class of select. Its action is blocking the aromatase enzyme, therefore blocking the production of estrogen. Since many forms of breast cancer are stimulated by estrogen, there is an assumption that by reducing the amount of estrogen, the progression of cancer can be stopped.
This is the main reason for using the drug instead of Nolvadex since the drug also blocks and the production of estrogen. The effects of Arimidex can be quite dramatic with a daily dose of 1 mg tablet the estrogen can be decreased in the body by more than 80%. With a powerful effect, postmenopausal women whose disease progressed after treatment with Nolvadex (tamoxifen citrate) can use this drug at a hormonal level. There is a possibility of the side effects and with no doubt be much more serious in premenopausal patients.
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